Sporadic Burkitt’s lymphoma presents as an isolated orbital disease

Ana Ibáñez Muñoz, Ana Ibáñez Muñoz, Ana Ibáñez Muñoz, M. Ester Lizuain Abadia, M. Ester Lizuain Abadia, Elena Delso Gil, Elena Delso Gil, Sara Velilla Osés, Sara Velilla Osés


Burkitt’s lymphoma is a highly aggressive non–Hodgkin’s lymphoma and the fastest growing, that accounts for 3% to 5% of all lymphomas.  Three clinically subtypes have been described:  endemic, sporadic, and immunodeficiency-associated.  The sporadic form typically presents as an abdominal mass.  Orbital involvement has rarely been reported.  In this case report, a 66-year-old man presented with a three-week history of vision loss and painful proptosis of the left eye.  Neuro-imaging revealed a well-circumscribed solid mass of the left orbit, for which a biopsy under general anesthesia was performed.   The diagnosis of Burkitt’s lymphoma was confirmed by immunohistochemistry.  Chemotherapy was initiated with good clinical outcome, though there was no improvement in his visual acuity.  In conclusion, Burkitt’s lymphoma must be considered in patients who present with painful proptosis and vision loss, as it is one of the fastest growing and chemosensitive malignancies, which can lead to irreversible vision loss.


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DOI: http://dx.doi.org/10.16964/er.v5i1.78


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