Conjunctival blue nevus
Keywords:conjunctiva, blue nevus, melanocytic proliferation.
AbstractThe authors report a case of a conjunctival blue nevus and review the literature pertaining to these pigmented lesions in this location, describing clinical and histological report of a patient with a blue nevus of the palpebral conjunctiva with a literature review. A 64-year-old white female was evaluated for a darkening pigmented lesion of the left lower palpebral conjunctiva. Examination revealed a 3 mm x 6mm blue-black lesion with sharply demarcated edges and an irregular border. Histopa - thology showed plump spindle-shaped, pigmented melanocytic cells revealing a branching network of dendritic processes with small, elongated, and hyperchromatic nuclei consistent with a common blue nevus. No recurrence was noted at 9-month follow-up. Blue nevi of the conjunctiva are lesions that have a low risk for malignant transformation but can appear clinically similar to primary acquired melanosis or melanoma. Blue nevi of the conjunctiva are rare and represent 0.5%-3.0% of pigmented conjunctival lesions. There was one reported case in a literature search of a malignant melanoma arising from a conjunctival cellular blue nevus. Treatment is complete wide excisional biopsy.
An Open Access Publication is one that meets the following two conditions:
1. The author(s) and copyright holder(s) grant(s) to all users a free, irrevocable, worldwide, perpetual right of access to, and a license to copy, use, distribute, transmit and display the work publicly and to make and distribute derivative works, in any digital medium for any responsible purpose, subject to proper attribution of authorship, as well as the right to make small numbers of printed copies for their personal use.
2. A complete version of the work and all supplemental materials, including a copy of the permission as stated above, in a suitable standard electronic format is deposited immediately upon initial publication in at least one online repository that is supported by an academic institution, scholarly society, government agency, or other well-established organization that seeks to enable open access, unrestricted distribution, interoperability, and long-term archiving.
Authors who publish with this journal agree to the following terms: 1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal. 2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal. 3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.